SCHEMBL11596189

SCHEMBL11596189

Cc1nc(C(=O)Cl)c(C)nc1C(=O)Cl

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.33
CA2 P00918 5/20 0.33
CA9 Q16790 5/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CA1 P00915 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27897265 0.95 CA12 (0.39) CA12CA2CA9ALDH1A1HPGD
SCHEMBL6387026 0.78 MAPT (0.52) ALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL2168269 0.73 CA12 (0.42) CA12CA2CA9ALDH1A1HPGD
SCHEMBL20039944 0.72 EGLN1 (0.37) ALDH1A1NPSR1
SCHEMBL7718725 0.71 KDM4E (0.44)
Hydrochloric Acid SCHEMBL11596190 0.71 CA12 (0.41) CA12CA2CA9ALDH1A1HPGD
SCHEMBL9959966 0.69
SCHEMBL3435829 0.69 SMN1; SMN2 (0.48) CA12CA2CA9SMN1; SMN2NPSR1
SCHEMBL2406658 0.69 CA12 (0.48) CA12CA2CA9ALDH1A1HPGD
SCHEMBL7015920 0.67 PPARD (0.35) ALDH1A1HPGDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed