Sugi Predict

Sugi Predict / Compounds / SCHEMBL2168269

SCHEMBL2168269

SCHEMBL2168269

Cc1nc(C(=O)O)c(C)nc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 3/20 0.42
▸ CA2 P00918 3/20 0.42
▸ CA9 Q16790 3/20 0.42
▸ ALDH1A1 P00352 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ HCAR2 Q8TDS4 3/20 0.39
▸ HPGD P15428 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ GABRP O00591 1/20 0.38
▸ GABRD O14764 1/20 0.38
▸ GABRA1 P14867 1/20 0.38
▸ GABRB1 P18505 1/20 0.38
▸ GABRG2 P18507 1/20 0.38
▸ GABRB3 P28472 1/20 0.38
▸ GABRA5 P31644 1/20 0.38
▸ GABRA3 P34903 1/20 0.38
▸ GABRA2 P47869 1/20 0.38
▸ GABRB2 P47870 1/20 0.38
▸ GABRA4 P48169 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11596190 0.97 CA12 (0.41) CA12CA2CA9ALDH1A1SMN1; SMN2
Water SCHEMBL28571228 0.97 CA12 (0.41) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL2406658 0.94 CA12 (0.48) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL29467764 0.94 CA12 (0.48) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL352388 0.88 ALDH1A1 (0.46) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL29415465 0.88 ALDH1A1 (0.46) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL31214286 0.85 ALDH1A1 (0.41) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL27231863 0.85 ALDH1A1 (0.41) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL12257174 0.85 GABRP (0.39) CA12CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL20298329 0.82 TDP1 (0.47) CA12CA2CA9ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072104-A1 METAL-ORGANIC FRAMEWORK MATERIAL AND PREPARATION METHOD THEREFOR 广东美的白色家电技术创新中心有限公司 2023-05-04 — — WO claimed
CN-114044913-A Metal-organic framework material and preparation method thereof 广东美的白色家电技术创新中心有限公司 2022-02-15 — — CN claimed
CN-107827827-A A kind of synthesis technique of H168 南京中医药大学 2018-03-23 — — CN claimed
CN-102060789-A Method for preparing 3, 6-dimethyl-2, 5-dipyrazinamide ZHANGJIAGANG CITY LANDISEN NEW MATERIAL TECHNOLOGY CO LTD 2011-05-18 — — CN claimed
EP-0425344-B1 Light polarizing materials and suspensions thereof RESEARCH FRONTIERS INC (US) 1994-05-18 — — EP claimed
EP-0425344-A2 Light polarizing materials and suspensions thereof RESEARCH FRONTIERS INCORPORATED (US) 1991-05-02 — — EP claimed
US-5002701-A Iodine and Halide Complex of a Pyrazinedicarboxylic Acid RESEARCH FRONTIERS INCORPORATED (US) 1991-03-26 — — US claimed
JP-3167290-A — — None — — JP disclosed
CN-115364822-B Preparation method and application of MOFs material 广东美的白色家电技术创新中心有限公司 2023-10-27 — — CN disclosed
CN-114044913-B Metal-organic framework material and preparation method thereof 广东美的白色家电技术创新中心有限公司 2023-05-30 — — CN disclosed
WO-2023072104-A1 METAL-ORGANIC FRAMEWORK MATERIAL AND PREPARATION METHOD THEREFOR 广东美的白色家电技术创新中心有限公司 2023-05-04 — — WO disclosed
CN-114044913-A Metal-organic framework material and preparation method thereof 广东美的白色家电技术创新中心有限公司 2022-02-15 — — CN disclosed
CN-108503598-A Supermolecular gel compound and synthetic method and the application in fluorine ion detection 天津大学 2018-09-07 — — CN disclosed
US-20080269484-A1 Metallic Compound and Organic Electroluminescence Device Comprising the Same SAMSUNG ELECTRONICS CO., LTD., (KR) 2008-10-30 — — US disclosed
US-20080269484-A1 Metallic Compound and Organic Electroluminescence Device Comprising the Same SAMSUNG ELECTRONICS CO., LTD., (KR) 2008-10-30 — — US disclosed
WO-2007078179-A1 METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2007-07-12 — — WO disclosed
US-5516463-A Method of making light-polarizing particles RESEARCH FRONTIERS INCORPORATED (US) 1996-05-14 — — US disclosed
EP-0635734-A2 Method of making light-polarizing particles RESEARCH FRONTIERS INCORPORATED (US) 1995-01-25 — — EP disclosed
JP-H03167290-A LIGHT POLARIZING MATERIAL AND SUSPENSION THEREOF RES FRONTIERS INC 1991-07-19 — — JP disclosed
US-4093622-A Pyridine esters of cyclopropane-carboxylic acid ZOECON CORPORATION (US) 1978-06-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269484-A1 Metallic Compound and Organic Electroluminescence Device Comprising the Same ROS1, MT-CO1, RER1 CA12 777/4885CA2 2073/4885CA9 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.