Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743305 | 0.80 | PDK2 (0.38) | EGLN1ALDH1A1 | |
| SCHEMBL15082052 | 0.79 | EGLN1 (0.42) | EGLN1NPSR1ALDH1A1MAPT | |
| SCHEMBL1831305 | 0.77 | EGLN1 (0.37) | EGLN1NPSR1ALDH1A1MAPT | |
| SCHEMBL13998902 | 0.74 | NPSR1 (0.54) | EGLN1NPSR1ALDH1A1MAPT | |
| SCHEMBL11596189 | 0.72 | CA12 (0.33) | NPSR1ALDH1A1 | |
| SCHEMBL6169773 | 0.70 | EGLN1 (0.34) | EGLN1 | |
| SCHEMBL27897265 | 0.69 | CA12 (0.39) | ALDH1A1 | |
| SCHEMBL77166 | 0.68 | LMNA (0.30) | — | |
| SCHEMBL5477906 | 0.65 | ALDH1A1 (0.40) | EGLN1ALDH1A1MAPT | |
| SCHEMBL13336077 | 0.62 | SMN1; SMN2 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091012-B1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | CENTREXION THERAPEUTICS CORP (US) | 2018-04-11 | — | — | EP | disclosed |