Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809545 | 0.96 | TTR (0.58) | TTRMAP4K4PTPRCEGFRALDH1A1 | |
| SCHEMBL2213544 | 0.96 | TTR (0.58) | TTRMAP4K4PTPRCEGFRALDH1A1 | |
| SCHEMBL36018 | 0.92 | TTR (0.62) | TTRPTPRCEGFRALDH1A1POLB | |
| SCHEMBL4620446 | 0.91 | MAP4K4 (0.56) | TTRMAP4K4PTPRCEGFRALDH1A1 | |
| SCHEMBL28397372 | 0.91 | MAP4K4 (0.59) | MAP4K4EGFRRARBRARGRXRA | |
| SCHEMBL29111668 | 0.91 | PTPRC (0.65) | TTRMAP4K4PTPRCEGFRALDH1A1 | |
| SCHEMBL27867340 | 0.90 | TP53 (0.55) | TTRPTPRCEGFRALDH1A1RARB | |
| SCHEMBL21271868 | 0.89 | KMO (0.59) | TTRMAP4K4EGFRALDH1A1RARB | |
| SCHEMBL3809549 | 0.89 | KMO (0.63) | TTRPTPRCALDH1A1RXRAPOLB | |
| SCHEMBL27883746 | 0.88 | TP53 (0.52) | TTRPTPRCEGFRALDH1A1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108835-A | Phenylated aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1978-08-22 | — | — | US | disclosed |