SCHEMBL28397372

SCHEMBL28397372

O=C(O)c1ccc(-c2cc(-c3ccccc3)ccc2-c2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.59
EGFR P00533 3/20 0.59
KMO O15229 1/20 0.55
TRIM24 O15164 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
RXRA P19793 4/20 0.53
RXRB P28702 3/20 0.53
RXRG P48443 1/20 0.53
BCL2 P10415 1/20 0.53
PDK2 Q15119 1/20 0.51
CYP2C8 P10632 1/20 0.50
CYP2C9 P11712 1/20 0.50
AXL P30530 2/20 0.49
SGK1 O00141 1/20 0.49
CAMKK2 Q96RR4 1/20 0.49
RARB P10826 1/20 0.49
RARG P13631 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4620446 0.93 MAP4K4 (0.56) MAP4K4EGFRKMOTRIM24TRIM33
SCHEMBL11596279 0.91 TTR (0.55) MAP4K4EGFRKMORXRACYP2C8
SCHEMBL2213544 0.90 TTR (0.58) MAP4K4EGFRKMORXRACYP2C8
SCHEMBL3809545 0.90 TTR (0.58) MAP4K4EGFRKMORXRACYP2C8
SCHEMBL28397371 0.88 EGFR (0.62) MAP4K4EGFRKMORXRARXRB
SCHEMBL17014850 0.88 EGFR (0.62) MAP4K4EGFRKMOTRIM24TRIM33
SCHEMBL21271868 0.87 KMO (0.59) MAP4K4EGFRKMOTRIM24TRIM33
SCHEMBL7789645 0.87 EGFR (0.69) MAP4K4EGFRKMOTRIM24TRIM33
SCHEMBL36018 0.86 TTR (0.62) EGFRKMOCYP2C8CYP2C9
SCHEMBL36017 0.86 TSHR (0.59) MAP4K4EGFRRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551372-A Moisture regulating composition and support material containing the same 菲利普莫里斯生产公司 2022-12-30 CN claimed
CN-115515708-A Package containing tobacco or nicotine products comprising a moisture regulating product 菲利普莫里斯生产公司 2022-12-23 CN claimed
CN-115551372-A Moisture regulating composition and support material containing the same 菲利普莫里斯生产公司 2022-12-30 CN disclosed
CN-115515708-A Package containing tobacco or nicotine products comprising a moisture regulating product 菲利普莫里斯生产公司 2022-12-23 CN disclosed
CN-111182964-A Chromium-based metal-organic frameworks for water adsorption related applications and gas storage 阿卜杜拉国王科技大学 2020-05-19 CN disclosed