Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595360 | 0.80 | NPSR1 (0.43) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL11595247 | 0.79 | NPSR1 (0.46) | MEN1KMT2AMAPTHTTCA9 | |
| SCHEMBL11596561 | 0.79 | LMNA (0.46) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL11593655 | 0.79 | MAPT (0.44) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL8684835 | 0.77 | MEN1 (0.43) | MEN1KMT2AMAPTHTTCA9 | |
| SCHEMBL11593747 | 0.77 | MAPT (0.40) | MEN1KMT2AMAPTHTTCA9 | |
| SCHEMBL8680760 | 0.77 | MEN1 (0.50) | MEN1KMT2AMAPTHTTCA9 | |
| SCHEMBL8682159 | 0.77 | MEN1 (0.41) | MEN1KMT2AMAPTHTTCA9 | |
| SCHEMBL11594939 | 0.76 | MAPT (0.49) | MEN1KMT2AMAPTHTTCA9 | |
| SCHEMBL1771870 | 0.75 | FTO (0.54) | MEN1KMT2AMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4078074-A | 2H-Chromene-2-spiro-3'-phthalides useful as horticultural and agricultural fungicides | RIKAGAKU KENKYUSHO AND MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JA) | 1978-03-07 | — | — | US | claimed |
| US-4078074-A | 2H-Chromene-2-spiro-3'-phthalides useful as horticultural and agricultural fungicides | RIKAGAKU KENKYUSHO AND MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JA) | 1978-03-07 | — | — | US | disclosed |