SCHEMBL11596342

SCHEMBL11596342

CC(CCc1ccccc1O)C1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.46
TAAR1 Q96RJ0 1/20 0.42
ESR1 P03372 1/20 0.41
HTR1A P08908 1/20 0.39
HSPA5 P11021 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
MPO P05164 4/20 0.38
TYR P14679 2/20 0.36
KDM4E B2RXH2 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27813202 0.83 ESR1 (0.43) HRH3TAAR1ESR1HSPA5MPO
SCHEMBL27813256 0.82 ESR1 (0.42) HRH3ESR1HSPA5ALDH1A1HTT
SCHEMBL27813229 0.82 ESR1 (0.42) HRH3ESR1HSPA5ALDH1A1HTT
SCHEMBL27520194 0.82 HRH3 (0.44) HRH3TAAR1ESR1HTR1AHSPA5
SCHEMBL16191445 0.78 HTT (0.54) TAAR1ALDH1A1HTT
SCHEMBL9950378 0.76 ALDH1A1 (0.38) ALDH1A1HTT
SCHEMBL678728 0.75 TAAR1 (0.54) HRH3TAAR1HTR1AHSPA5MPO
SCHEMBL14027541 0.75 DHODH (0.51) ALDH1A1HTTKDM4E
SCHEMBL27813163 0.74 HRH3 (0.39) HRH3ESR1HSPA5ALDH1A1HTT
SCHEMBL9949401 0.74 ALDH1A1 (0.34) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4115355-A SUBSTITUTED PHENOLS NIPPON ZEON CO. LTD. (JP) 1978-09-19 US disclosed