Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596342 | 0.82 | HRH3 (0.46) | HRH3TAAR1HSPA5MPOKDM4E | |
| SCHEMBL5880952 | 0.81 | HTT (0.48) | TAAR1KDM4ETP53 | |
| SCHEMBL13280870 | 0.81 | HTR2A (0.45) | TAAR1OPRM1OPRD1OPRK1KDM4E | |
| SCHEMBL4564333 | 0.79 | HTT (0.50) | TAAR1OPRM1OPRD1OPRK1TP53 | |
| SCHEMBL14612202 | 0.77 | SCN9A (0.47) | KDM4E | |
| SCHEMBL14036137 | 0.77 | SCN9A (0.47) | KDM4E | |
| SCHEMBL10369056 | 0.77 | TSHR (0.46) | KDM4ETP53 | |
| SCHEMBL13976392 | 0.76 | TAAR1 (0.58) | HRH3TAAR1HSPA5MPOHTR1A | |
| SCHEMBL22060634 | 0.75 | SIGMAR1 (0.36) | OPRM1OPRD1OPRK1SLC6A4IDO1 | |
| SCHEMBL10826137 | 0.74 | ALOX15 (0.46) | TAAR1OPRM1OPRK1KDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247508-C | Ether kind compound containing cyclopentyl and its synthesis method and application | CHINA PETROCHEMICAL CORP (CN) | 2006-03-29 | — | — | CN | disclosed |
| CN-1597650-A | Ether kind compound containing cyclopentyl and its synthesis method and application | CHINA PETROCHEMICAL CORP (CN) | 2005-03-23 | — | — | CN | disclosed |