Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599527 | 0.84 | SIGMAR1 (0.42) | SIGMAR1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11621042 | 0.83 | SIGMAR1 (0.54) | SIGMAR1KCNH2HTTSLC6A2SLC6A4 | |
| SCHEMBL11619490 | 0.81 | SIGMAR1 (0.43) | SIGMAR1KCNH2CACNA1I | |
| SCHEMBL11705675 | 0.74 | KCNH2 (0.41) | SIGMAR1KCNH2GRIA4ESRRGCA1 | |
| SCHEMBL11708685 | 0.72 | EP300 (0.39) | SIGMAR1KCNH2GRIA4ESRRGCA1 | |
| SCHEMBL11619842 | 0.68 | MAOB (0.43) | SIGMAR1 | |
| SCHEMBL6948447 | 0.66 | KCNH2 (0.55) | SIGMAR1KCNH2GRIA4ESRRG | |
| SCHEMBL2879490 | 0.66 | KCNH2 (0.58) | SIGMAR1KCNH2GRIA4ESRRG | |
| SCHEMBL5126879 | 0.66 | GBA1 (0.55) | HTTMEN1KMT2A | |
| SCHEMBL14606688 | 0.66 | GBA1 (0.55) | HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070400-A | MICROBIOCIDES, ALGICIDES | MERCK & CO., INC. (US) | 1978-01-24 | — | — | US | claimed |