Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31573982 | 0.83 | KCNH2 (0.67) | KCNH2SIGMAR1GRIA4TP53TSHR | |
| SCHEMBL12197969 | 0.82 | FDFT1 (0.54) | KCNH2DAO | |
| SCHEMBL10597831 | 0.82 | KCNH2 (0.49) | KCNH2SIGMAR1GRIA4TP53TSHR | |
| SCHEMBL115558 | 0.82 | KCNH2 (0.49) | KCNH2SIGMAR1GRIA4TP53TSHR | |
| SCHEMBL582269 | 0.79 | ESRRG (0.51) | KCNH2SIGMAR1GRIA4TP53TSHR | |
| SCHEMBL13778186 | 0.79 | NR1H4 (0.48) | KCNH2GRIA4TP53TSHRLMNA | |
| SCHEMBL3090240 | 0.78 | GRIA4 (0.46) | KCNH2SIGMAR1GRIA4TP53TSHR | |
| SCHEMBL13008878 | 0.78 | NR1H4 (0.50) | KCNH2SIGMAR1LMNAESRRGNR1H4 | |
| SCHEMBL6944831 | 0.78 | TP53 (0.53) | KCNH2SIGMAR1GRIA4TP53TSHR | |
| SCHEMBL7456580 | 0.78 | KCNH2 (0.59) | KCNH2SIGMAR1GRIA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |