Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | OGFRL1 | Q5TC84 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595954 | 0.89 | OPRM1 (0.48) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| SCHEMBL11596389 | 0.87 | OPRM1 (0.49) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| SCHEMBL11604174 | 0.87 | OPRM1 (0.44) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| SCHEMBL11602587 | 0.86 | OPRM1 (0.43) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| SCHEMBL11650527 | 0.85 | OPRM1 (0.45) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| SCHEMBL11596132 | 0.84 | OPRM1 (0.46) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| SCHEMBL11598173 | 0.84 | OPRM1 (0.46) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| Acetic Acid SCHEMBL11624482 | 0.82 | OPRM1 (0.49) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| Acetic Acid SCHEMBL11822954 | 0.82 | OPRM1 (0.49) | OPRM1OGFRL1OPRD1OPRK1OPRL1 | |
| SCHEMBL11598186 | 0.82 | OPRM1 (0.49) | OPRM1OGFRL1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076831-A | Pyrano[3,4-b]-indole derivatives, pharmaceutical compositions and methods of use | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |
| US-4070371-A | ANTIINFLAMMATORY, ANALGESIC, ANTIBACTERIAL, FUNGICIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-4012417-A | ACID CATALYSTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-3974179-A | ANTIINFLAMMATORY, ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |
| US-3939178-A | ANTIINFLAMMATORY, ANALGESIC, BACTERICIDE, FUNGICIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |