Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.45 |
| ▸ | THRA | P10827 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605410 | 0.91 | THRB (0.50) | THRBTHRAALDH1A1LMNAKMT2A | |
| SCHEMBL9626488 | 0.85 | FOLH1 (0.47) | ALDH1A1LMNAKMT2AMAPTFOLH1 | |
| SCHEMBL10664651 | 0.80 | FOLH1 (0.53) | ALDH1A1LMNAKMT2AMEN1FOLH1 | |
| SCHEMBL27790363 | 0.79 | THRB (0.46) | THRBTHRAKMT2AMEN1 | |
| Acrylic Acid SCHEMBL5308916 | 0.78 | FOLH1 (0.54) | THRBTHRAALDH1A1MAPTFOLH1 | |
| SCHEMBL11604500 | 0.76 | KDM4E (0.51) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL19834620 | 0.76 | FOLH1 (0.40) | ALDH1A1LMNAKMT2AMEN1FOLH1 | |
| SCHEMBL10347642 | 0.75 | AKT1 (0.61) | THRBALDH1A1LMNAKMT2AAKT1 | |
| SCHEMBL11606521 | 0.75 | HCRTR1 (0.53) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL12802459 | 0.75 | THRB (0.38) | THRBTHRAALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115413-A | ACID FREE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-19 | — | — | US | disclosed |