SCHEMBL11599009

SCHEMBL11599009

CC(=O)Oc1cc(C(C)(C)C)ccc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.56
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 2/20 0.51
CYP2C19 P33261 2/20 0.51
USP2 O75604 1/20 0.51
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.51
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
BACE1 P56817 1/20 0.41
CYP2C9 P11712 1/20 0.41
LMNA P02545 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
GAA P10253 1/20 0.40
TSHR P16473 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL30274386 0.91 KDM4E (0.48) ACHEKDM4EALDH1A1CYP2C19USP2
SCHEMBL132968 0.87 MRGPRX4 (0.47) ACHEKDM4EALDH1A1CYP2C19USP2
SCHEMBL21551571 0.87 CA1 (0.42) ACHEKDM4EALDH1A1CYP2C19USP2
SCHEMBL17953132 0.85 KDM4E (0.55) KDM4EALDH1A1CYP2C19USP2HPGD
SCHEMBL21551572 0.83 CYP2C9 (0.42) ACHEKDM4EALDH1A1CYP2C19USP2
SCHEMBL15459991 0.83 KDM4E (0.74) KDM4EALDH1A1CYP2C19USP2HPGD
SCHEMBL28418778 0.82 ALDH1A1 (0.52) KDM4EALDH1A1CYP2C19USP2HPGD
SCHEMBL12118572 0.81 TSHR (0.58) KDM4EALDH1A1CYP2C19USP2HPGD
SCHEMBL22928144 0.81 CYP2C19 (0.49) KDM4EALDH1A1CYP2C19USP2HPGD
SCHEMBL13021636 0.79 KDM4E (0.44) ACHEKDM4EALDH1A1CYP2C19USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4069271-A ISOMERIZATION, DEHYDROGENATION, OXIDATION, REDUCTION, TRANSITION METAL STANDARD OIL COMPANY (INDIANA) (US) 1978-01-17 US disclosed
US-4005049-A FOR ISOMERIZATION, DEHYDROGENATION, REDUCTION AND MILD OXIDATION STANDARD OIL COMPANY (INDIANA) (US) 1977-01-25 US disclosed