SCHEMBL21551571

SCHEMBL21551571

Cc1ccc(C(C)(C)C)cc1OC(=O)C(=O)Oc1cc(C(C)(C)C)ccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CYP2C9 P11712 2/20 0.41
ACHE P22303 2/20 0.41
LMNA P02545 1/20 0.41
CYP2C19 P33261 2/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
TDP1 Q9NUW8 4/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 1/20 0.39
KDM4E B2RXH2 2/20 0.39
RXRB P28702 1/20 0.39
TTR P02766 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C8 P10632 1/20 0.39
CHRM1 P11229 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21551572 0.91 CYP2C9 (0.42) CA1CA2CA9CYP2C9ACHE
SCHEMBL11599009 0.87 ACHE (0.56) CA1CA2CA9CYP2C9ACHE
Methacrylic Acid SCHEMBL30274386 0.82 KDM4E (0.48) CA1CA2CA9CYP2C9ACHE
SCHEMBL10587671 0.78 TRPV1 (0.36) CA1CA2CA9CYP2C9ACHE
SCHEMBL25477260 0.78 KDM4E (0.44) CA1CA2CA9CYP2C9LMNA
SCHEMBL21551646 0.76 TSHR (0.53) CYP2C9ACHELMNATDP1HSD17B10
SCHEMBL2625766 0.76 KDM4E (0.43) CA1CA2CA9TDP1ALDH1A1
SCHEMBL13580642 0.76 CYP2C19 (0.66) CYP2C9LMNACYP2C19MRGPRX4TDP1
SCHEMBL15887460 0.76 MRGPRX4 (0.48) CA1CA2CA9LMNACYP2C19
SCHEMBL11903131 0.75 CA1 (0.40) CA1CA2CA9CYP2C9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019216355-A1 METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL 高砂香料工業株式会社 (JP) 2019-11-14 WO disclosed