Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13105958 | 0.84 | HTT (0.50) | ALDH1A1HTTXBP1TAS1R3TAS1R1 | |
| SCHEMBL2448483 | 0.82 | HTT (0.49) | ALDH1A1HTTXBP1TAS1R3TAS1R1 | |
| SCHEMBL31262315 | 0.82 | HTT (0.49) | ALDH1A1HTTXBP1TAS1R3TAS1R1 | |
| SCHEMBL29045700 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HTTXBP1TAS1R3TAS1R1 | |
| SCHEMBL7691863 | 0.79 | HTT (0.47) | ALDH1A1HTTXBP1KMT2ATSHR | |
| SCHEMBL27261538 | 0.79 | HTT (0.51) | ALDH1A1HTTXBP1KMT2ATSHR | |
| SCHEMBL7696586 | 0.78 | HTT (0.48) | ALDH1A1HTTXBP1KMT2AMEN1 | |
| SCHEMBL769134 | 0.78 | KMT2A (0.51) | ALDH1A1HTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3412231 | 0.78 | PRMT5 (0.52) | ALDH1A1HTTXBP1TAS1R3TAS1R1 | |
| SCHEMBL31613076 | 0.78 | PRMT5 (0.52) | ALDH1A1HTTXBP1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082807-A | REACTING AN AROMATIC COMPOUND WITH AN ACETOACETYL FLUORIDE; HYDROGEN FLUORIDE | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |
| US-3937737-A | CHEMICAL INTERMEDIATES, DYES, PLASTICS, METAL COMPLEXES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |