Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666042 | 0.91 | PIN1 (0.51) | TSHRHTR2CSLC6A3L3MBTL1GAA | |
| SCHEMBL13105958 | 0.81 | HTT (0.50) | HTTALDH1A1TSHRHPGDBLM | |
| SCHEMBL29045700 | 0.81 | ALDH1A1 (0.58) | HTTALDH1A1TSHRHPGDBLM | |
| SCHEMBL7696586 | 0.81 | HTT (0.48) | HTTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2796237 | 0.80 | HTT (0.54) | HTTALDH1A1TSHRBLMMEN1 | |
| SCHEMBL2792830 | 0.80 | HTT (0.54) | HTTALDH1A1TSHRBLMMEN1 | |
| SCHEMBL29706163 | 0.80 | HTT (0.54) | HTTALDH1A1TSHRBLMMEN1 | |
| SCHEMBL29608780 | 0.80 | HTT (0.54) | HTTALDH1A1TSHRBLMMEN1 | |
| SCHEMBL242244 | 0.80 | HTT (0.54) | HTTALDH1A1TSHRBLMMEN1 | |
| SCHEMBL29484110 | 0.80 | HTT (0.54) | HTTALDH1A1TSHRBLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024630-A1 | PHARMACEUTICAL COMPOUNDS USEFUL AS MODULATORS OF ENDOCANNABINOID-MEDIATED RESPONSE | ELI LILLY AND COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |