Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599212 | 1.00 | RAPGEF4 (0.43) | RAPGEF4IDO1KDM4ETSHRPTGS1 | |
| SCHEMBL734962 | 0.87 | TSHR (0.56) | KDM4ETSHRSLC2A1LMNA | |
| SCHEMBL31362160 | 0.87 | TSHR (0.56) | KDM4ETSHRSLC2A1LMNA | |
| SCHEMBL9231410 | 0.87 | TSHR (0.56) | KDM4ETSHRSLC2A1LMNA | |
| SCHEMBL4626208 | 0.86 | TSHR (0.55) | KDM4ETSHRSLC2A1LMNA | |
| SCHEMBL4626199 | 0.86 | TSHR (0.55) | KDM4ETSHRSLC2A1LMNA | |
| SCHEMBL5661601 | 0.85 | PTGS1 (0.48) | KDM4ETSHRPTGS1PTGS2LMNA | |
| SCHEMBL5661600 | 0.85 | PTGS1 (0.48) | KDM4ETSHRPTGS1PTGS2LMNA | |
| SCHEMBL30047330 | 0.85 | PTGS1 (0.48) | KDM4ETSHRPTGS1PTGS2LMNA | |
| SCHEMBL736304 | 0.85 | MMP8 (0.53) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4102671-A | HERBICIDES | SHELL OIL COMPANY (US) | 1978-07-25 | — | — | US | disclosed |