Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878388 | 0.85 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL18974286 | 0.83 | — | — | |
| SCHEMBL13391048 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL13536717 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL2237235 | 0.74 | — | — | |
| SCHEMBL12666595 | 0.74 | LMNA (0.43) | — | |
| SCHEMBL713742 | 0.74 | — | — | |
| SCHEMBL223936 | 0.74 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL5114656 | 0.74 | — | — | |
| SCHEMBL12858606 | 0.72 | MAPK1 (0.37) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077983-A | PROGESTATIONAL ACTIVITY | HOFFMANN-LA ROCHE, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4061679-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4059612-A | Substituted indanones | HOFFMANN-LA ROCHE, INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4053486-A | STEREOSPECIFIC TOTAL STEROIDAL SYNTHESIS VIA SUBSTITUTED C/D-TRANS INDANONES | HOFFMANN-LA ROCHE INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4052413-A | STEREOSPECIFIC TOTAL STEROIDAL SYNTHESIS VIA SUBSTITUTED C/D-TRANS INDANONES | HOFFMANN-LA ROCHE, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4048195-A | Process of synthesizing substituted indanones | HOFFMANN-LA ROCHE INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-3985733-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3984473-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3965117-A | Stereospecific total steroidal synthesis via substituted c/d-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3950389-A | Stereospecific total steroidal synthesis via substituted C/D-trans indanones | HOFFMANN-LA ROCHE INC. (US) | 1976-04-13 | — | — | US | disclosed |