⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107546 | 0.85 | — | — | |
| SCHEMBL18427 | 0.78 | — | — | |
| SCHEMBL13391048 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL13536717 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL11599232 | 0.74 | MAPK1 (0.33) | — | |
| SCHEMBL223936 | 0.74 | MAPK1 (0.33) | — | |
| SCHEMBL713742 | 0.74 | — | — | |
| SCHEMBL12666595 | 0.74 | LMNA (0.43) | — | |
| SCHEMBL15943072 | 0.72 | MAPK1 (0.42) | — | |
| SCHEMBL12858606 | 0.72 | MAPK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984427-A | Preparation of vinyl lactones and corresponding Mannich bases | HOFFMANN-LA ROCHE INC. (US) | 1976-10-05 | — | — | US | claimed |
| US-7355053-B2 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-08 | — | — | US | disclosed |
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | US | disclosed |
| EP-1556346-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037787-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-06 | — | — | WO | disclosed |
| US-5130356-A | Addition of small amounts of diphenoquinone or diphenohydroquinone derivatives; compact disc substrates | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0385109-A2 | Shaped article for optical uses | BASF Aktiengesellschaft (DE) | 1990-09-05 | — | — | EP | disclosed |