Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871540 | 0.92 | CTSC (0.64) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL9118550 | 0.89 | CTSC (0.61) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL6906379 | 0.89 | CTSC (0.62) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL28081233 | 0.89 | CTSC (0.62) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL2183137 | 0.88 | CTSC (0.61) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL8892785 | 0.87 | CTSC (0.59) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL2195208 | 0.87 | CTSC (0.59) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL2192888 | 0.86 | KDM4E (0.60) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL8397051 | 0.86 | KDM4E (0.60) | CTSCKDM4EMAPTMEN1LMNA | |
| SCHEMBL8397046 | 0.86 | KDM4E (0.60) | CTSCKDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082736-A | NOVEL IMMUNOLOGICAL ADJUVANT COMPOUNDS AND METHODS OF PREPARATION THEREOF | SYNTEX (U.S.A.) INC. (US) | 1978-04-04 | — | — | US | claimed |