Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192888 | 0.97 | KDM4E (0.60) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL8397051 | 0.97 | KDM4E (0.60) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL8397046 | 0.97 | KDM4E (0.60) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL27871540 | 0.93 | CTSC (0.64) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL11382333 | 0.92 | OPRM1 (0.59) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL11765780 | 0.92 | OPRM1 (0.59) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL11382901 | 0.92 | OPRM1 (0.59) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL9057338 | 0.92 | KDM4E (0.55) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL9118550 | 0.88 | CTSC (0.61) | CTSCKDM4EMEN1MAPTTSHR | |
| SCHEMBL1652435 | 0.88 | ACE (0.53) | CTSCECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624894-A | Brain-enhanced delivery of neuroactive peptides by sequential metabolism | UNIVERSITY OF FLORIDA (US) | 1997-04-29 | — | — | US | disclosed |