Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 3/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598826 | 0.91 | PPARA (0.43) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL11597955 | 0.91 | BACE1 (0.46) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL11598192 | 0.90 | REN (0.50) | REN | |
| SCHEMBL11598951 | 0.89 | CCKBR (0.46) | CTSSCTSKRENKMT2AKLK5 | |
| SCHEMBL11647964 | 0.88 | AKT1 (0.42) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL11173700 | 0.87 | PSEN1 (0.44) | AKT1KMT2AKLK5 | |
| SCHEMBL11599238 | 0.86 | ACE (0.57) | ACECTSSCTSKCTSL | |
| SCHEMBL11597513 | 0.86 | SYK (0.41) | ACECTSSCTSK | |
| SCHEMBL28485547 | 0.84 | ACE (0.56) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL28485548 | 0.84 | ACE (0.56) | ACECTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082736-A | NOVEL IMMUNOLOGICAL ADJUVANT COMPOUNDS AND METHODS OF PREPARATION THEREOF | SYNTEX (U.S.A.) INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4082735-A | NOVEL IMMUNOLOGICAL ADJUVANT COMPOUNDS AND METHODS OF PREPARATION THEREOF | SYNTEX (U.S.A.) INC. (US) | 1978-04-04 | — | — | US | disclosed |