Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | REN | P00797 | 7/20 | 0.59 |
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598856 | 0.94 | BCL2 (0.57) | CTSLRENPTPN1 | |
| SCHEMBL10887447 | 0.93 | PPARA (0.53) | CTSLRENCTSSCTSKCTSB | |
| SCHEMBL11599337 | 0.93 | PPARA (0.53) | CTSLRENCTSSCTSKCTSB | |
| SCHEMBL14997847 | 0.93 | PPARA (0.53) | CTSLRENCTSSCTSKCTSB | |
| SCHEMBL11598828 | 0.92 | REN (0.53) | CTSLRENCTSSCTSKPTPN1 | |
| Hydrochloric Acid SCHEMBL11597785 | 0.92 | PPARA (0.52) | CTSLRENCTSSCTSKCTSB | |
| SCHEMBL11597960 | 0.91 | REN (0.50) | CTSLRENCTSSCTSK | |
| SCHEMBL17446708 | 0.91 | CTSS (0.56) | CTSLRENCTSSCTSKCTSB | |
| SCHEMBL11598195 | 0.90 | REN (0.62) | CTSLRENCTSSCTSKPTPN1 | |
| SCHEMBL11050756 | 0.90 | CTSS (0.60) | CTSLRENCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082736-A | NOVEL IMMUNOLOGICAL ADJUVANT COMPOUNDS AND METHODS OF PREPARATION THEREOF | SYNTEX (U.S.A.) INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4082735-A | NOVEL IMMUNOLOGICAL ADJUVANT COMPOUNDS AND METHODS OF PREPARATION THEREOF | SYNTEX (U.S.A.) INC. (US) | 1978-04-04 | — | — | US | disclosed |