Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.57 |
| ▸ | SCN1A | P35498 | 3/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530814 | 0.88 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL25219221 | 0.84 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL7614425 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL2066147 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL290075 | 0.80 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL17071880 | 0.80 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL4796436 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL6377512 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL1422822 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A | |
| SCHEMBL27511961 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CHRM2SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |