SCHEMBL2066147

SCHEMBL2066147

NCC(c1ccccc1)c1ccccn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.59
SLC6A4 P31645 6/20 0.59
SLC6A3 Q01959 5/20 0.59
HTR2A P28223 5/20 0.58
TAAR1 Q96RJ0 1/20 0.58
CHRM2 P08172 5/20 0.57
SCN1A P35498 3/20 0.57
SCN2A Q99250 3/20 0.57
SCN3A Q9NY46 3/20 0.57
ALDH1A1 P00352 3/20 0.53
CHRNB2 P17787 1/20 0.48
CHRNA4 P43681 1/20 0.48
CYP1A2 P05177 1/20 0.47
TSHR P16473 3/20 0.47
LMNA P02545 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
KDM4E B2RXH2 1/20 0.47
RAB9A P51151 1/20 0.47
CHRM1 P11229 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1422822 1.00 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
SCHEMBL27511961 1.00 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
Hydrochloric Acid SCHEMBL7927468 0.98 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
Hydrochloric Acid SCHEMBL16702791 0.98 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
Hydrochloric Acid SCHEMBL7864529 0.98 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
SCHEMBL6890882 0.91 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
SCHEMBL6933091 0.90 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
SCHEMBL22461294 0.88 SLC6A2 (0.62) SLC6A2SLC6A4SLC6A3HTR2ACHRM2
SCHEMBL20777760 0.88 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
SCHEMBL7073817 0.86 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165057-A liquid 米利肯工业有限公司 2023-12-05 CN claimed
CN-112739758-A Liquid, method for producing the same and use thereof 博奇斯催化剂(英国)有限公司 2021-04-30 CN claimed
CN-107709658-B Oxidation process 卡特克塞尔科技有限公司 2021-04-09 CN claimed
EP-3307940-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP claimed
CN-108431079-B Coating composition curable by oxidation 卡特克塞尔有限公司 2020-12-04 CN claimed
CN-107709533-B Oxidation process 卡特克塞尔科技有限公司 2020-09-18 CN claimed
EP-2791352-A1 GABR-A2 DIAGNOSTIC Astrazeneca AB (SE) 2014-10-22 EP claimed
CN-103459520-A Antiskinning compositions OMG UK TECHNOLOGY LTD 2013-12-18 CN claimed
WO-2013088135-A1 GABR-A2 DIAGNOSTIC ASTRAZENECA AB (SE) 2013-06-20 WO claimed
US-20090233920-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2009-09-17 US claimed
EP-1907359-A2 3,5-SUBSTITUTED PIPERIDINE DERIVATIVES EFFECTIVE ON RENIN-RELATED DISORDERS Novartis AG (CH) 2008-04-09 EP claimed
WO-2007017652-A2 ARYLAKYLAMINES FOR THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2007-02-15 WO claimed
WO-2007006534-A2 PIPERIDINE DERIVATIVES USEFUL IN THE DIAGNOSTIC AND THERAPEUTIC TREATMENT OF DISEASES DEPENDING ON RENIN ACTIVITY NOVARTIS AG (CH) 2007-01-18 WO claimed
EP-1506277-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2005-02-16 EP claimed
WO-2003097780-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2003-11-27 WO claimed
WO-2000063174-A1 NOVEL PROCESS ASTRAZENECA AB (SE) 2000-10-26 WO claimed
CN-118215715-A Method for improving resin properties 博奇斯有限公司 2024-06-18 CN disclosed
CN-117165057-A liquid 米利肯工业有限公司 2023-12-05 CN disclosed
US-4948802-A H2 AGONISTS, TREATING HEART DISEASE HEUMANN PHARMA GMBH & CO. (DE) 1990-08-14 US disclosed
EP-0302164-A1 Guanidine-carboxylic-acid esters, method for their preparation and medicines containing these compounds HEUMANN PHARMA GMBH & CO (DE) 1989-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233920-A1 ORGANIC COMPOUNDS REN, ACE, AGTR1 SLC6A2 449/4885SLC6A4 586/4885SLC6A3 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.