Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599476 | 0.84 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL25219221 | 0.82 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL17295946 | 0.80 | IDO1 (0.49) | HTR2AALDH1A1IDO1TDO2KDM4E | |
| SCHEMBL7605334 | 0.80 | IDO1 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL11968461 | 0.80 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL6268312 | 0.75 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL9530814 | 0.73 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL5949434 | 0.70 | GRIN2D (0.47) | SLC6A4CYP2D6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16915442 | 0.69 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CHRM2KCNH2 | |
| SCHEMBL9186509 | 0.69 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035123-A1 | New substituted pyridine or piperidine compounds | ADIR ET COMPAGNIE | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035123-A1 | New substituted pyridine or piperidine compounds | OPRD1, CNR1, HRH4 | SLC6A2 2824/4885SLC6A4 2045/4885SLC6A3 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.