Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935824 | 0.84 | CTBP2 (0.58) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL3626720 | 0.82 | CTBP2 (0.46) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL2240152 | 0.79 | AKR1B1 (0.59) | TAAR1 | |
| SCHEMBL80264 | 0.79 | CTBP2 (0.53) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL363774 | 0.79 | CTBP2 (0.53) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL21851724 | 0.78 | SHBG (0.49) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL7676855 | 0.78 | ALDH1A1 (0.44) | KMT2AMEN1HPGDALDH1A1NPC1 | |
| SCHEMBL12731524 | 0.77 | CTBP2 (0.51) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL8861870 | 0.77 | CTBP2 (0.51) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL3629093 | 0.77 | CTBP2 (0.51) | CTBP2KMT2AMEN1MAPTSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082807-A | REACTING AN AROMATIC COMPOUND WITH AN ACETOACETYL FLUORIDE; HYDROGEN FLUORIDE | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |
| US-4036605-A | CATALYZING OXIDATION OF HYDROCARBONS WITH A B-KETOENOLATE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1977-07-19 | — | — | US | disclosed |
| US-3937737-A | CHEMICAL INTERMEDIATES, DYES, PLASTICS, METAL COMPLEXES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |