Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158336 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL6598611 | 0.76 | PEPD (0.33) | MAPTALDH1A1 | |
| SCHEMBL7067134 | 0.76 | CA12 (0.38) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL11410354 | 0.76 | CA1 (0.38) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL11404951 | 0.76 | L3MBTL1 (0.44) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL1415961 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL7068047 | 0.73 | TP53 (0.43) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL11694848 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL11410301 | 0.70 | ALDH1A1 (0.43) | SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL11601668 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29834-E | PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | claimed |