Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862429 | 0.77 | POLB (0.37) | ALDH1A1PDE4DPTGER2EPHX2PGR | |
| SCHEMBL9976701 | 0.77 | POLB (0.37) | ALDH1A1PDE4DPTGER2EPHX2PGR | |
| SCHEMBL862237 | 0.77 | POLB (0.37) | ALDH1A1PDE4DPTGER2EPHX2PGR | |
| SCHEMBL12087973 | 0.77 | POLB (0.39) | ALDH1A1PTGER3PTGER4PTGER2EPHX2 | |
| SCHEMBL18965531 | 0.76 | POLB (0.38) | ALDH1A1PTGER3PTGER4PTGER2EPHX2 | |
| SCHEMBL11599490 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599487 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599493 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL13119839 | 0.73 | PDE4D (0.51) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL3008851 | 0.73 | PDE4D (0.51) | KDM4EALDH1A1HKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981867-B1 | METHOD FOR PREPARING PROSTAGLANDIN DERIVATIVE | R-TECH UENO LTD (JP) | 2017-06-14 | — | — | EP | disclosed |