SCHEMBL11599685

SCHEMBL11599685

C=C(CC(Cl)CO)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.48
TET3 O43151 1/20 0.48
TET1 Q8NFU7 1/20 0.48
GRIK1 P39086 1/20 0.46
GRIK2 Q13002 1/20 0.46
GRM1 Q13255 1/20 0.46
GRM2 Q14416 1/20 0.46
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4940094 0.81 TET2 (0.48) TET2TET3TET1GRIK1GRIK2
SCHEMBL9336384 0.77 TET2 (0.35) TET2TET3TET1GRIK1GRIK2
SCHEMBL9746301 0.77
SCHEMBL8043434 0.74 TET2 (0.52) TET2TET3TET1GRIK1GRIK2
SCHEMBL7521331 0.74
SCHEMBL7520601 0.74
SCHEMBL7525449 0.74
SCHEMBL570959 0.73 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
SCHEMBL2772613 0.73
SCHEMBL9056207 0.73 TET2 (0.50) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4124395-A POLYMER HAVING CARBOXYL GROUPS OR GROUPS WHICH FORM CARBOXYL GROUPS ON HYDROLYSIS AND, AS ADDITION POLYMERIZABLE MONOMER, HEXAHYDRO-1,3,5-TRIACRYL-S-TRIAZINE FUJI PHOTO FILM CO., LTD. (JP) 1978-11-07 US disclosed
US-3935342-A POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-27 US disclosed