SCHEMBL8043434

SCHEMBL8043434

C=C(CC(CO)C(O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.52
TET3 O43151 1/20 0.52
TET1 Q8NFU7 1/20 0.52
GRIK1 P39086 1/20 0.45
GRIK2 Q13002 1/20 0.45
GRM1 Q13255 1/20 0.45
GRM2 Q14416 1/20 0.45
OR51E2 Q9H255 1/20 0.33
PDE4A P27815 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919200 0.80 TET2 (0.50) TET2TET3TET1GRIK1GRIK2
SCHEMBL9066693 0.78 OR51E2 (0.38) TET2TET3TET1GRIK1OR51E2
Acrylic Acid SCHEMBL2471255 0.77 ALOX15 (0.50) TET2TET3TET1GRIK1GRIK2
SCHEMBL570959 0.76 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
SCHEMBL9000232 0.74 TET2 (0.54) TET2TET3TET1GRIK1GRIK2
SCHEMBL11599685 0.74 TET2 (0.48) TET2TET3TET1GRIK1GRIK2
Glycerin SCHEMBL12504632 0.74 TET2 (0.54) TET2TET3TET1GRIK1GRIK2
SCHEMBL2158348 0.72
SCHEMBL9056207 0.71 TET2 (0.50) TET2TET3TET1GRIK1GRIK2
SCHEMBL27956532 0.71 TET2 (0.50) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786495-B1 Thermoplastic polyester resin stretched film OJI YUKA SYNT PAPER CO LTD (JP) 2000-04-12 EP disclosed
US-5677055-A POLYESTER RESIN, MODIFIED OLEFIN OBTAINED BY GRAFT POLYMERIZING ALPHA, BETA-UNSATURATED CARBOXYLATE MONOMER CONTAINING HYDROXYL GROUPS AND AROMATIC VINYL MONOMER ONTO OLEFIN, POLYETHYLENE, EPOXY RESIN; RECORDING PAPER SUPPORT OJI-YUKA SYNTHETIC PAPER CO., LTD. (JP) 1997-10-14 US disclosed
EP-0786495-A2 Thermoplastic polyester resin stretched film OJI-YUKA SYNTHETIC PAPER CO., LTD. (JP) 1997-07-30 EP disclosed