Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL5879928 | 0.96 | SIGMAR1 (0.57) | SIGMAR1DRD2DRD4DRD3TSHR | |
| Toluene SCHEMBL19468536 | 0.94 | SIGMAR1 (0.55) | SIGMAR1DRD2DRD4DRD3TSHR | |
| Toluene SCHEMBL28217025 | 0.88 | SIGMAR1 (0.50) | SIGMAR1DRD2DRD4DRD3TSHR | |
| Toluene SCHEMBL8635446 | 0.84 | LMNA (0.58) | SIGMAR1TSHRLMNAALOX12ACHE | |
| Toluene SCHEMBL14698429 | 0.84 | SIGMAR1 (0.50) | SIGMAR1DRD2DRD4DRD3TSHR | |
| Heptane SCHEMBL3728317 | 0.82 | LMNA (0.55) | TSHRLMNAALOX12ACHEHTT | |
| Phenol SCHEMBL6882765 | 0.81 | SIGMAR1 (0.55) | SIGMAR1DRD2DRD4DRD3TSHR | |
| Toluene SCHEMBL28456683 | 0.81 | TSHR (0.48) | SIGMAR1DRD2DRD4DRD3TSHR | |
| Biphenyl SCHEMBL7742046 | 0.80 | SIGMAR1 (0.59) | SIGMAR1DRD2DRD4DRD3TSHR | |
| O-Xylene SCHEMBL29228911 | 0.80 | SIGMAR1 (0.53) | SIGMAR1DRD2DRD4DRD3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083828-A | Preparation of polyphenylene oxides by the oxidative coupling of a phenolic monomer in the presence of a manganese salt, base and a secondary amine | GENERAL ELECTRIC COMPANY (US) | 1978-04-11 | — | — | US | disclosed |