Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.61 |
| ▸ | PPARG | P37231 | 6/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602527 | 0.95 | PPARA (0.58) | PPARAPPARGCYP2C19CYP2C9PPARD | |
| SCHEMBL11601202 | 0.91 | PPARG (0.54) | PPARAPPARGPPARDKCNN4KMT2A | |
| SCHEMBL11599887 | 0.91 | PPARA (0.68) | PPARAPPARGCYP2C19CYP2C9PPARD | |
| SCHEMBL11600978 | 0.85 | PPARA (0.61) | PPARAPPARGCYP2C19CYP2C9PPARD | |
| SCHEMBL11602031 | 0.85 | PPARA (0.61) | PPARAPPARGCYP2C19CYP2C9PPARD | |
| SCHEMBL11600958 | 0.84 | PPARG (0.57) | PPARAPPARGPPARDKMT2AMEN1 | |
| SCHEMBL5691818 | 0.84 | PPARG (0.61) | PPARAPPARGCYP2C19CYP2C9PPARD | |
| SCHEMBL27638956 | 0.81 | PPARG (0.59) | PPARAPPARGCYP2C19CYP1A2KMT2A | |
| SCHEMBL11600576 | 0.80 | PPARA (0.62) | PPARAPPARGCYP2C19CYP2C9PPARD | |
| SCHEMBL11394121 | 0.80 | PPARA (0.58) | PPARAPPARGCYP2C19CYP2C9PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072754-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-02-07 | — | — | US | disclosed |