Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602527 | 0.88 | PPARA (0.58) | PPARGPPARAPPARDMEN1KMT2A | |
| SCHEMBL11602402 | 0.87 | PPARG (0.57) | PPARGNR4A2PPARAPPARDMAOB | |
| SCHEMBL11601217 | 0.87 | PPARG (0.57) | PPARGNR4A2PPARAPPARDMAOB | |
| SCHEMBL11601202 | 0.84 | PPARG (0.54) | PPARGPPARAPPARDMEN1KMT2A | |
| SCHEMBL11600039 | 0.84 | PPARA (0.61) | PPARGPPARAPPARDMEN1KMT2A | |
| SCHEMBL11733799 | 0.82 | PPARG (0.72) | PPARGNR4A2PPARAPPARDMAOB | |
| SCHEMBL11755471 | 0.81 | PPARG (0.49) | PPARGNR4A2PPARAPPARDMAOB | |
| SCHEMBL11756569 | 0.80 | MAOB (0.51) | PPARGNR4A2PPARAPPARDMAOB | |
| SCHEMBL11597711 | 0.78 | PPARG (0.52) | PPARGNR4A2PPARAPPARDMAOB | |
| SCHEMBL27638956 | 0.77 | PPARG (0.59) | PPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072754-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-02-07 | — | — | US | disclosed |