Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602527 | 0.95 | PPARA (0.58) | PPARGPPARAPPARDKCNN4MEN1 | |
| SCHEMBL11600039 | 0.91 | PPARA (0.61) | PPARGPPARAPPARDKCNN4MEN1 | |
| SCHEMBL11565233 | 0.87 | PPARA (0.53) | PPARGPPARAPPARDMEN1ALDH1A1 | |
| SCHEMBL11601984 | 0.85 | PPARA (0.54) | PPARGPPARAPPARDMEN1NPC1 | |
| SCHEMBL11600781 | 0.85 | PPARA (0.57) | PPARGPPARAPPARDMEN1ALDH1A1 | |
| SCHEMBL11600958 | 0.84 | PPARG (0.57) | PPARGPPARAPPARDFFAR1MEN1 | |
| SCHEMBL5691818 | 0.84 | PPARG (0.61) | PPARGPPARAPPARDKCNN4MEN1 | |
| SCHEMBL27638956 | 0.81 | PPARG (0.59) | PPARGPPARALTA4HMEN1ALDH1A1 | |
| SCHEMBL11599887 | 0.81 | PPARA (0.68) | PPARGPPARAPPARDMEN1NPC1 | |
| SCHEMBL11394121 | 0.80 | PPARA (0.58) | PPARGPPARAPPARDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072754-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-02-07 | — | — | US | disclosed |