Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706157 | 0.92 | ADRA2A (0.40) | KMT2AMTNR1AMTNR1BADRA2AADRA2B | |
| SCHEMBL9344689 | 0.76 | CA1 (0.56) | CA12CA1CA2CA4CA7 | |
| SCHEMBL3256317 | 0.76 | MAOB (0.34) | ADRA2AADRA2BADRA2CCYP1A2CYP2D6 | |
| SCHEMBL10245022 | 0.76 | CA1 (0.44) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11886646 | 0.76 | CA1 (0.44) | CA12CA1CA2CA4CA7 | |
| SCHEMBL10429856 | 0.75 | ADRA2A (0.43) | CA4MTNR1AMTNR1BADRA2AADRA2B | |
| SCHEMBL17210749 | 0.74 | CA1 (0.59) | CA12CA1CA2CA4CA7 | |
| SCHEMBL9446669 | 0.74 | HPGD (0.38) | KMT2AALDH1A1SLC6A2CYP1A2MEN1 | |
| SCHEMBL105697 | 0.73 | CA1 (0.65) | CA12CA1CA2CA4CA7 | |
| SCHEMBL31433095 | 0.73 | CA1 (0.65) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073917-A | Local anesthetics tertiary aminoalkoxyphenyl ethers | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1978-02-14 | — | — | US | disclosed |