Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15412521 | 0.98 | ADRA2A (0.42) | ADRA2AADRA2BPGRHTR2AHRH1 | |
| SCHEMBL9706129 | 0.89 | ALDH1A3 (0.39) | ADRA2AADRA2BPGRHTR2AHRH1 | |
| SCHEMBL11682289 | 0.87 | BCHE (0.49) | ADRA2AADRA2BHTR2AHRH1KCNH2 | |
| SCHEMBL9706148 | 0.86 | KDM4E (0.39) | ADRA2AADRA2BPGRHTR2AHRH1 | |
| SCHEMBL5529419 | 0.86 | LTA4H (0.50) | L3MBTL1LMNABCHELTA4HHTT | |
| Hydrochloric Acid SCHEMBL7123972 | 0.84 | LTA4H (0.49) | L3MBTL1LMNABCHELTA4HHTT | |
| SCHEMBL12610940 | 0.84 | CYP2D6 (0.56) | ADRA2AADRA2BPGRHTR2AKCNH2 | |
| Benzofuran SCHEMBL5035533 | 0.82 | KCNA3 (0.33) | ADRA2AADRA2BPGRHTR2AHRH1 | |
| SCHEMBL3327499 | 0.82 | ALDH1A3 (0.34) | ADRA2AADRA2BPGRHTR2AHRH1 | |
| SCHEMBL9706157 | 0.81 | ADRA2A (0.40) | ADRA2AADRA2BPGRHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2164801-A | — | — | None | — | — | JP | disclosed |
| US-8962869-B2 | Process for synthesizing keto benzofuran derivatives | SANOFI (FR) | 2015-02-24 | — | — | US | disclosed |
| US-20140046078-A1 | PROCESS FOR SYNTHESIZING KETO BENZOFURAN DERIVATIVES | SANOFI (FR) | 2014-02-13 | — | — | US | disclosed |
| EP-2688879-A1 | METHOD FOR SYNTHESIZING KETOBENZOFURAN DERIVATIVES | SANOFI (FR) | 2014-01-29 | — | — | EP | disclosed |
| US-20140018553-A1 | PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES | SANOFI (FR) | 2014-01-16 | — | — | US | disclosed |
| WO-2012127174-A1 | METHOD FOR SYNTHESIZING KETOBENZOFURAN DERIVATIVES | SANOFI (FR) | 2012-09-27 | — | — | WO | disclosed |
| JP-H02164801-A | PLANT DYE-INCREASING AGENT | NITTO BAION KK | 1990-06-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046078-A1 | PROCESS FOR SYNTHESIZING KETO BENZOFURAN DERIVATIVES | CYP3A4, CYP2F1, DHPS | ADRA2A 2944/4885ADRA2B 2714/4885PGR 3651/4885 |
| US-20140018553-A1 | PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES | CYP2F1, CYP3A4, CYP2B6 | ADRA2A 2249/4885ADRA2B 1891/4885PGR 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.