SCHEMBL11600239

SCHEMBL11600239

Cc1cccc(NC(=O)OOc2cccc(N(C)C(=O)O)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.50
ALDH1A1 P00352 2/20 0.50
FAAH O00519 1/20 0.50
CYP3A4 P08684 1/20 0.50
BCHE P06276 1/20 0.49
ACHE P22303 1/20 0.49
HSD17B10 Q99714 1/20 0.43
HSD17B1 P14061 2/20 0.42
HSD17B2 P37059 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419739 0.88 ALDH1A1 (0.66) MAPK1ALDH1A1FAAHCYP3A4BCHE
SCHEMBL8983603 0.77 BCHE (0.66) MAPK1ALDH1A1FAAHCYP3A4BCHE
SCHEMBL27714131 0.75 ALDH1A1 (0.50) MAPK1ALDH1A1FAAHCYP3A4BCHE
SCHEMBL7576788 0.74 MEN1 (0.48) MAPK1ALDH1A1BCHEACHEHSD17B10
SCHEMBL30229852 0.74 HSD17B1 (0.57) MAPK1ALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL1684295 0.74 HSD17B1 (0.57) MAPK1ALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL11600235 0.74 SMN1; SMN2 (0.45) CYP3A4HSD17B1HSD17B2SMN1; SMN2NPC1
SCHEMBL11326986 0.73 ALDH1A1 (0.62) MAPK1ALDH1A1FAAHCYP3A4BCHE
Ammonia Solution, Strong SCHEMBL28786422 0.73 HSD17B1 (0.55) MAPK1ALDH1A1CYP3A4HSD17B10HSD17B1
Phenyl M-Tolylcarbamate SCHEMBL29739712 0.72 ALDH1A1 (0.78) MAPK1ALDH1A1FAAHCYP3A4BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-53020427-A None JP disclosed
JP-S5320427-A COMPOSITION FOR HERBICIDES KUMIAI CHEM IND CO LTD 1978-02-24 JP disclosed