SCHEMBL1160034

SCHEMBL1160034

Cc1cccc(C(C)(C)C)c1-c1ccccc1-c1ccccc1-c1c(C)cccc1C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.50
GABRB2 P47870 1/20 0.50
CA2 P00918 2/20 0.41
TSHR P16473 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MYC P01106 1/20 0.40
PDK2 Q15119 1/20 0.40
HTR7 P34969 2/20 0.39
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
ACHE P22303 1/20 0.36
KIF11 P52732 1/20 0.35
PTPN5 P54829 1/20 0.35
CYP3A4 P08684 1/20 0.33
DPP4 P27487 1/20 0.33
NPC1 O15118 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1160002 0.93 GABRA1 (0.48) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL28215180 0.89 GABRA1 (0.44) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL9247985 0.85 CA2 (0.46) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL14877302 0.84 GABRA1 (0.60) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL1160035 0.82 GABRA1 (0.42) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL29235924 0.79 GABRA1 (0.50) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL26499113 0.79 GABRA1 (0.46) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL22227385 0.78 GABRA1 (0.42) GABRA1GABRB2CA2ALDH1A1TDP1
SCHEMBL1160003 0.77 GABRA1 (0.41) GABRA1GABRB2CA2TSHRALDH1A1
SCHEMBL8091209 0.77 MYC (0.48) CA2TSHRALDH1A1TDP1MYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183311-B2 Liquid phosphite composition derived from cresols CHEMTURA CORPORATION (US) 2012-05-22 US disclosed
WO-2011014211-A1 LIQUID PHOSPHITE COMPOSITION DERIVED FROM META-CRESOLS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
US-20100076125-A1 LIQUID PHOSPHITE COMPOSITION DERIVED FROM CRESOLS CHEMTURA CORPORATION (US) 2010-03-25 US disclosed