SCHEMBL11600930

SCHEMBL11600930

CCCC(=O)C(CC)CS

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CA2 P00918 3/20 0.37
FOLH1 Q04609 1/20 0.37
MAPK1 P28482 1/20 0.37
FFAR3 O14843 2/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
CA1 P00915 1/20 0.35
TSHR P16473 2/20 0.35
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9883262 0.85 CES2 (0.45) CES2CES1CA2MAPK1FFAR3
SCHEMBL2465225 0.78 CES2 (0.39) CES2CES1CA2MAPK1FFAR3
SCHEMBL20838325 0.78 HDAC1 (0.50) CES2CES1CA2MAPK1FFAR3
SCHEMBL28747829 0.74 CA2 (0.40) CES2CES1CA2MAPK1FFAR3
SCHEMBL812448 0.74 CA2 (0.61) CA2MAPK1CA1
SCHEMBL21343979 0.74 SLC1A3 (0.38) CES2CES1CA2MAPK1FFAR3
SCHEMBL328134 0.73 USP2 (0.43) CA2MAPK1CA1TSHRUSP2
SCHEMBL8423880 0.73 CA2 (0.54) CA2MAPK1CA1
SCHEMBL8860533 0.72 CES2 (0.43) CES2CES1MAPK1FFAR3HDAC3
SCHEMBL9582293 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4119788-A ODORS, FLAVORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-10-10 US disclosed
US-4107197-A KETONE REACTED WITH SULFURYL CHLORIDE, ALPHA-CHLORO KETONE REACTED WITH ALKALI METAL COMPOUND INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-08-15 US disclosed
US-4097396-A Soaps and detergents containing alpha-oxy(oxo)sulfides as perfumes INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 1978-06-27 US disclosed
US-4097615-A ORGANOLEPTIC, AROMA AND TASTE ENHANCING INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-06-27 US disclosed
US-4097532-A ENHANCING FLAVOR AND AROMA INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-06-27 US disclosed
US-4094824-A α-Oxy(oxo) sulfides in perfume INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-06-13 US disclosed
US-4088697-A 3-PROPYLTHIO-4-HEPTANOL; FOODSTUFF FLAVORS OR ODORANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-05-09 US disclosed
US-4083862-A α-Oxy(oxo) sulfides and ethers INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-04-11 US disclosed
US-4065408-A α-Oxy(oxo) sulfide perfume and cologne compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-27 US disclosed
US-4061796-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-06 US disclosed
US-4061795-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-06 US disclosed
US-4055691-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-25 US disclosed
US-4053655-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US disclosed
US-4053654-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US disclosed
US-4045491-A PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-30 US disclosed
US-4044164-A BERRY, CEREAL, NUT, BROCCOLI, ONION, CITRUS, JASMIN, MILK CARAMEL, GRAPE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-23 US disclosed