Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313311 | 0.89 | MAPT (0.59) | KMT2AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11601176 | 0.85 | KMT2A (0.52) | KMT2AMAPTCYP1A2CYP2C9MEN1 | |
| SCHEMBL11601247 | 0.82 | KMT2A (0.50) | KMT2AMAPTCYP1A2CYP2C9MEN1 | |
| SCHEMBL11602907 | 0.81 | MAPT (0.48) | KMT2AMAPTCYP1A2CYP2C19RAB9A | |
| SCHEMBL11601121 | 0.78 | LMNA (0.56) | KMT2AMAPTPOLBTP53LMNA | |
| SCHEMBL28519521 | 0.77 | KMT2A (0.35) | KMT2AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11602961 | 0.76 | MAPT (0.54) | KMT2AMAPTCYP2C9CYP2C19MEN1 | |
| SCHEMBL11404290 | 0.76 | KMT2A (0.41) | KMT2AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28388499 | 0.76 | KMT2A (0.41) | KMT2AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11601679 | 0.75 | NPC1 (0.41) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070536-A | Process for the preparation of 4-benzoylpyrazole derivatives | SANKYO COMPANY LIMITED (JA) | 1978-01-24 | — | — | US | disclosed |