Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602961 | 0.84 | MAPT (0.54) | NPC1RAB9APKMMAPTLMNA | |
| SCHEMBL11653261 | 0.84 | MAPT (0.50) | PKMMAPTGAAKMT2AALOX15 | |
| SCHEMBL25476901 | 0.83 | ALDH1A1 (0.36) | MAPTKMT2AALOX15MEN1ALDH1A1 | |
| SCHEMBL11601484 | 0.79 | CYP3A4 (0.41) | NPC1RAB9APKMMAPTLMNA | |
| SCHEMBL11602902 | 0.78 | MAPT (0.57) | MAPTLMNAGAAKMT2AMEN1 | |
| SCHEMBL11313311 | 0.78 | MAPT (0.59) | NPC1RAB9APKMMAPTLMNA | |
| SCHEMBL11601176 | 0.76 | KMT2A (0.52) | NPC1RAB9APKMMAPTLMNA | |
| SCHEMBL11601247 | 0.75 | KMT2A (0.50) | RAB9AMAPTLMNAGAAKMT2A | |
| SCHEMBL29629307 | 0.75 | GAA (0.40) | NPC1RAB9AMAPTGAAKMT2A | |
| SCHEMBL11600960 | 0.75 | KMT2A (0.46) | NPC1RAB9AMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070536-A | Process for the preparation of 4-benzoylpyrazole derivatives | SANKYO COMPANY LIMITED (JA) | 1978-01-24 | — | — | US | disclosed |