Terephthalamide

Terephthalamide

SCHEMBL1160108

NC(=O)c1ccc(C(=O)N2CCCCCCCCCCCC2)cc1.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 9/20 0.80
ALDH1A1 P00352 4/20 0.80
CA12 O43570 2/20 0.64
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
CA7 P43166 2/20 0.64
CA9 Q16790 2/20 0.64
CA14 Q9ULX7 2/20 0.64
MEN1 O00255 1/20 0.61
TSHR P16473 1/20 0.61
KMT2A Q03164 1/20 0.61
MAOA P21397 1/20 0.60
MAPK1 P28482 1/20 0.59
MLYCD O95822 2/20 0.58
USP2 O75604 1/20 0.58
MAPT P10636 1/20 0.57
LMNA P02545 1/20 0.57
MBTD1 Q05BQ5 3/20 0.56
L3MBTL3 Q96JM7 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170330 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL367947 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL1194042 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL367513 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL367607 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL1160398 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
Terephthalamide SCHEMBL13724808 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL11857269 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL4560822 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2
SCHEMBL1159865 1.00 HPGD (0.80) HPGDALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2307504-B1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS DU PONT (US) 2015-07-08 EP claimed
CN-111225940-B Polymerization process 杜邦聚合物公司 2023-10-10 CN disclosed
EP-2861660-B1 THERMOPLASTIC MELT-MIXED COMPOSITION WITH AMINO ACID HEAT STABILIZER DU PONT (US) 2018-09-05 EP disclosed
EP-2531704-B1 MUFFLER WITH INTEGRATED CATALYTIC CONVERTER AND POLYMERIC MUFFLER BODY DU PONT (US) 2018-05-23 EP disclosed
EP-2307482-B1 LONG-TERM HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS DU PONT (US) 2017-01-25 EP disclosed
EP-2841504-B1 THERMOPLASTIC POLYAMIDE COMPOSITION DU PONT (US) 2016-11-30 EP disclosed
EP-2307480-B1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS DU PONT (US) 2016-08-17 EP disclosed
US-9080034-B2 Thermoplastic melt-mixed composition with amino acid heat stabilizer E I DU PONT DE NEMOURS AND COMPANY (US) 2015-07-14 US disclosed
EP-2307504-B1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS DU PONT (US) 2015-07-08 EP disclosed
EP-2861660-A1 THERMOPLASTIC MELT-MIXED COMPOSITION WITH AMINO ACID HEAT STABILIZER E. I. Du Pont de Nemours and Company (US) 2015-04-22 EP disclosed
WO-2010014801-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed
WO-2010014795-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed
WO-2010014785-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed
US-20100029819-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100029821-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100029815-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100028580-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100028581-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
WO-2010014791-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed
WO-2010014790-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed