Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA7 | P43166 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MLYCD | O95822 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170330 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL1194042 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL367513 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL367607 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL1160398 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| Terephthalamide SCHEMBL1160108 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| Terephthalamide SCHEMBL13724808 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL11857269 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL4560822 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL1159865 | 1.00 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | claimed |
| EP-1628972-A1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-01 | — | — | EP | claimed |
| US-20040235824-A1 | Indazole-derivatives as factor Xa inhibitors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | US | claimed |
| WO-2004101556-A1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | claimed |
| EP-1479675-A1 | Indazole-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2004-11-24 | — | — | EP | claimed |
| EP-3860975-B1 | MODULATORS OF HEMOGLOBIN FOR THE TREATMENT OF SICKLE CELL DISEASE | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-10-18 | — | — | EP | disclosed |
| US-20230079764-A1 | Polymerization Process | DUPONT POLYMERS INC (US) | 2023-03-16 | — | — | US | disclosed |
| CN-111183174-B | Glass fiber reinforced resin molded article | 日东纺绩株式会社 | 2022-10-04 | — | — | CN | disclosed |
| CN-114144473-A | Polyamide resin composition and molded article obtained by molding same | 东丽株式会社 | 2022-03-04 | — | — | CN | disclosed |
| US-11254082-B2 | Multi-layer tube | UBE INDUSTRIES, LTD. (JP) | 2022-02-22 | — | — | US | disclosed |
| CN-113817157-A | Semi-aromatic polyamide polycondensation catalyst and preparation method thereof | 四川大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-113150269-A | Semi-aromatic polyamide copolymer and preparation thereof | 上海庚彩新材料科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20120016077-A1 | POLYAMIDE RESIN, POLYAMIDE RESIN COMPOSITION, AND MOLDED ARTICLE COMPRISING SAME | TORAY INDUSTRIES INC. (JP) | 2012-01-19 | — | — | US | disclosed |
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | disclosed |
| US-7365088-B2 | Indazole-derivatives as factor Xa inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-04-29 | — | — | US | disclosed |
| EP-1628972-A1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-01 | — | — | EP | disclosed |
| US-20040235824-A1 | Indazole-derivatives as factor Xa inhibitors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | US | disclosed |
| WO-2004101556-A1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |
| EP-1479675-A1 | Indazole-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2004-11-24 | — | — | EP | disclosed |
| CN-1336919-A | Phenylphenanthridines with PDE-IV inhibiting activity | BYK GULDEN LOMBERG CHEM FAB (DE) | 2002-02-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235824-A1 | Indazole-derivatives as factor Xa inhibitors | F11, F12, F5 | HPGD 678/4885ALDH1A1 1259/4885CA12 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.