Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049259 | 0.85 | MAPT (0.65) | MAPTGAAHPGDRAB9AEPHX2 | |
| SCHEMBL11603089 | 0.82 | MAPT (0.61) | MAPTGAAHPGDRAB9AEPHX2 | |
| SCHEMBL4110940 | 0.80 | MAPT (0.86) | MAPTGAAHPGDRAB9AEPHX2 | |
| SCHEMBL3953245 | 0.80 | MAPT (0.59) | MAPTGAAHPGDRAB9AEPHX2 | |
| SCHEMBL28133706 | 0.79 | MAPT (0.77) | MAPTGAAHPGDRAB9AHTT | |
| SCHEMBL27395957 | 0.79 | MAPT (0.50) | MAPTGAAHPGDRAB9AEPHX2 | |
| SCHEMBL11031785 | 0.78 | MAPT (0.57) | MAPTGAAHPGDRAB9AEPHX2 | |
| SCHEMBL1689206 | 0.78 | EPHX2 (0.68) | MAPTGAAEPHX2HTTL3MBTL1 | |
| SCHEMBL20734732 | 0.77 | MAPT (0.65) | MAPTGAAHPGDRAB9AEPHX2 | |
| SCHEMBL20734734 | 0.77 | MAPT (0.65) | MAPTGAAHPGDRAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |