Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.86 |
| ▸ | HPGD | P15428 | 3/20 | 0.86 |
| ▸ | RAB9A | P51151 | 3/20 | 0.86 |
| ▸ | GAA | P10253 | 2/20 | 0.86 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | SCN1A | P35498 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23518443 | 0.90 | RAB9A (0.76) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL22924879 | 0.89 | RAB9A (0.76) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL23518557 | 0.86 | HPGD (0.81) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL20734732 | 0.85 | MAPT (0.65) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL28049259 | 0.85 | MAPT (0.65) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL20734734 | 0.85 | MAPT (0.65) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL4299260 | 0.83 | RAB9A (0.68) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL16395827 | 0.83 | MAPT (0.63) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL10962729 | 0.82 | HPGD (0.62) | MAPTHPGDRAB9AGAAMEN1 | |
| SCHEMBL5649258 | 0.82 | RAB9A (0.67) | MAPTHPGDRAB9AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | claimed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | claimed |
| JP-59048403-A | — | — | None | — | — | JP | disclosed |
| US-11827638-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-28 | — | — | US | disclosed |
| US-11827638-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-28 | — | — | US | disclosed |
| EP-3675858-B1 | IMIDAZO[1,5-A]PYRAZINE COMPOUNDS AND COMPOSITIONS FOR IRE1 INHIBITION | OPTIKIRA LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| CN-115556441-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| CN-115556446-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| US-20210206768-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2021-07-08 | — | — | US | disclosed |
| US-10981911-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JANSSEN PHARMACEUTICA NV (BE) | 2021-04-20 | — | — | US | disclosed |
| US-10981899-B2 | Inhibitors of soluble adenylyl cyclase | CORNELL UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-20120149683-A1 | SUBSTITUTED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC | 2012-06-14 | — | — | US | disclosed |
| US-8093260-B2 | Aporphine derivatives and pharmaceutical use thereof | STANDARD CHEM. & PHARM. CO., LTD. (TW) | 2012-01-10 | — | — | US | disclosed |
| US-20090318489-A1 | Aporphine compounds and pharmaceutical use thereof | STANDARD CHEM. & PHARM. CO., LTD. (TW) | 2009-12-24 | — | — | US | disclosed |
| US-20090318488-A1 | Pharmaceutically acceprable salts of aporphine compounds of carboxyl group-containing agents and methods for preparing the same | STANDARD CHEM. & PHARM. CO., LTD. (TW) | 2009-12-24 | — | — | US | disclosed |
| US-20090231240-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE | FUJI XEROX CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-7560480-B2 | Alkyl-containing 5-acylindolinones, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-14 | — | — | US | disclosed |
| US-7358373-B2 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070032484-A1 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC | 2007-02-08 | — | — | US | disclosed |
| JP-S5948403-A | HERBICIDE FOR PADDY FIELD | YASHIMA CHEM IND CO LTD | 1984-03-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827638-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JAK1, JAK2, JAK3 | MAPT 3052/4885HPGD 833/4885RAB9A 2090/4885 |
| US-10981899-B2 | Inhibitors of soluble adenylyl cyclase | PDE7A, PDE6C, ADCYAP1R1 | MAPT 3506/4885HPGD 448/4885RAB9A 1285/4885 |
| US-20070032484-A1 | Cathepsin K inhibitors | CTSK, CTSS, CTSF | MAPT 3356/4885HPGD 3156/4885RAB9A 407/4885 |
| US-20210206768-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JAK1, JAK2, JAK3 | MAPT 3052/4885HPGD 833/4885RAB9A 2090/4885 |
| US-20090318489-A1 | Aporphine compounds and pharmaceutical use thereof | IAPP, OPRL1, AGER | MAPT 466/4885HPGD 451/4885RAB9A 3716/4885 |
| US-20090318488-A1 | Pharmaceutically acceprable salts of aporphine compounds of carboxyl group-containing agents and methods for preparing the same | IAPP, GPR119, AMY2A | MAPT 1473/4885HPGD 461/4885RAB9A 1868/4885 |
| US-10981911-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JAK1, JAK2, JAK3 | MAPT 3052/4885HPGD 833/4885RAB9A 2090/4885 |
| US-20120149683-A1 | SUBSTITUTED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OF DIABETES | DPP4, DPP3, DPP7 | MAPT 4030/4885HPGD 1338/4885RAB9A 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.