Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.68 |
| ▸ | KDM1A | O60341 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CDK9 | P50750 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235727 | 0.93 | HDAC4 (0.61) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL8089206 | 0.91 | HDAC4 (0.67) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL27538195 | 0.90 | EPHX2 (0.63) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL175602 | 0.90 | EPHX2 (0.63) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL19026741 | 0.89 | HDAC4 (0.58) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL19026946 | 0.89 | L3MBTL1 (0.75) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL307290 | 0.89 | KMT2A (0.61) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL3342586 | 0.87 | L3MBTL1 (0.80) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL14964154 | 0.86 | EPHX2 (0.59) | EPHX2HDAC4HDAC1HDAC7HDAC11 | |
| SCHEMBL3021545 | 0.86 | MAPT (0.67) | EPHX2HDAC4HDAC1HDAC7HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693529-A | Synthesis method of 2-aza [2.2.2] octane compound | 河南师范大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116425904-A | Supported Ziegler-Natta catalyst and preparation method and application thereof | 山东京博石油化工有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-111463445-B | Modified carbon material, all-vanadium redox flow battery, and preparation method and application thereof | 上海电气集团股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114195671-A | Asymmetric malonanilide compound and synthesis method thereof | 河南师范大学 | 2022-03-18 | — | — | CN | claimed |
| EP-1896395-A2 | MODIFIED MALONATE DERIVATIVES | Merck & Co., Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2007002248-A2 | MODIFIED MALONATE DERIVATIVES | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-6780887-B1 | TREATING AND/OR PREVENTING ISCHEMIA, PATHOLOGIES ASSOCIATED WITH ISCHEMIA OR PATHOLOGIES ASSOCIATED WITH MITOCHONDRIAL DEFICIENCIES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-08-24 | — | — | US | claimed |
| US-20020049190-A1 | Pharmaceutical compositions comprising metal complexes | ANORMED INC. (CA) | 2002-04-25 | — | — | US | claimed |
| EP-1163247-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES | ANORMED INC. (CA) | 2001-12-19 | — | — | EP | claimed |
| EP-1092432-A1 | Anti-ischemic compounds | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (S.C.R.A.S.) (FR) | 2001-04-18 | — | — | EP | claimed |
| WO-2000056743-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES | ANORMED INC. (CA) | 2000-09-28 | — | — | WO | claimed |
| EP-0512211-B1 | Process for the preparation of substituted malonic ester anilides and malonic acid monoanilides | HUELS CHEMISCHE WERKE AG (DE) | 1995-04-12 | — | — | EP | claimed |
| US-5334747-A | Reacting substituted malonic acid dialkyl ester with aniline in presence of stoichiometric amount of alkali alcoholate, neutralizing product with acid, saponifying with water | HULS AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | claimed |
| JP-2250053-A | — | — | None | — | — | JP | disclosed |
| US-12427798-B2 | Heat-sensitive recording composition | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2025-09-30 | — | — | US | disclosed |
| US-20250001788-A1 | HEAT-SENSITIVE RECORDING COMPOSITION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2025-01-02 | — | — | US | disclosed |
| EP-0029719-A1 | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers | MONSANTO COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| EP-0012112-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |
| US-3932182-A | An organic photoconductive composition comprising an organic photoconductive compound and a sensitizing compound having an active methylene group | MITSUBISHI PAPER MILLS, LTD. (JA) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049190-A1 | Pharmaceutical compositions comprising metal complexes | CFD, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F12 | EPHX2 1014/4885HDAC4 2477/4885HDAC1 1744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.