⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159851 | 1.00 | — | — | |
| SCHEMBL9443124 | 1.00 | — | — | |
| SCHEMBL7270865 | 0.99 | — | — | |
| SCHEMBL7278139 | 0.98 | HTR3A (0.53) | — | |
| SCHEMBL7270771 | 0.98 | HTR3A (0.53) | — | |
| SCHEMBL9443039 | 0.98 | HTR3A (0.53) | — | |
| SCHEMBL7276197 | 0.87 | HTR3E (0.49) | — | |
| SCHEMBL8084193 | 0.85 | CHRNA7 (0.42) | — | |
| SCHEMBL7279707 | 0.85 | HTR3E (0.49) | — | |
| SCHEMBL7269201 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614225-B2 | Process for the purification of palonosetron or its salt | DR. REDDY'S LABORATORIES LIMITED (IN) | 2013-12-24 | — | — | US | disclosed |
| WO-2011013095-A1 | PROCESSES FOR THE PREPARATION OF PALONOSETRON | RANBAXY LABORATORIES LIMITED (IN) | 2011-02-03 | — | — | WO | disclosed |
| US-20080058367-A1 | PROCESS FOR THE PURIFICATION OF PALONOSETRON OR ITS SALT | DR. REDDY'S LABORATORIES, INC. | 2008-03-06 | — | — | US | disclosed |
| EP-0430190-B1 | New tricyclic compounds | SYNTEX INC (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5202333-A | Tricyclic 5-HT3 receptor antagonists | SYNTEX (U.S.A.) INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0430190-A2 | New tricyclic compounds | SYNTEX (U.S.A.) INC. (US) | 1991-06-05 | — | — | EP | disclosed |