Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | UGCG | Q16739 | 2/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081325 | 0.82 | EPHX2 (0.57) | EPHX2TEAD3FAAHL3MBTL1HDAC1 | |
| SCHEMBL25269510 | 0.82 | EPHX2 (0.57) | EPHX2TEAD3FAAHL3MBTL1HDAC1 | |
| SCHEMBL19032713 | 0.82 | EPHX2 (0.57) | EPHX2TEAD3FAAHL3MBTL1HDAC1 | |
| SCHEMBL11047003 | 0.79 | FAAH (0.44) | FAAH | |
| SCHEMBL25210921 | 0.78 | MAPT (0.54) | EPHX2FAAHL3MBTL1HDAC3HDAC1 | |
| SCHEMBL25213662 | 0.78 | MAPT (0.54) | EPHX2FAAHL3MBTL1HDAC3HDAC1 | |
| SCHEMBL25212789 | 0.78 | MAPT (0.54) | EPHX2FAAHL3MBTL1HDAC3HDAC1 | |
| SCHEMBL8984536 | 0.78 | MAPT (0.54) | EPHX2FAAHL3MBTL1HDAC3HDAC1 | |
| SCHEMBL25246359 | 0.76 | EPHX2 (0.52) | EPHX2TEAD3FAAHGBA1UGCG | |
| SCHEMBL25215220 | 0.76 | EPHX2 (0.52) | EPHX2TEAD3FAAHGBA1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098815-A | BRONCHODILATOR AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |