Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601260 | 0.89 | FFAR4 (0.65) | RELAFFAR4FFAR1FAAHGPR84 | |
| SCHEMBL11602007 | 0.89 | FFAR4 (0.65) | RELAFFAR4FFAR1FAAHGPR84 | |
| SCHEMBL11603766 | 0.87 | CA12 (0.55) | RELAFFAR4FFAR1FAAHGPR84 | |
| SCHEMBL11602334 | 0.84 | ACE2 (0.49) | RELAFFAR4FFAR1FAAHGPR84 | |
| SCHEMBL11601301 | 0.84 | DGKA (0.47) | RELAFFAR4FFAR1CA2CA12 | |
| SCHEMBL19066822 | 0.81 | FFAR4 (0.71) | FFAR4FFAR1FAAHGPR84NFKB1 | |
| SCHEMBL21585875 | 0.81 | FFAR4 (0.71) | FFAR4FFAR1FAAHGPR84NFKB1 | |
| SCHEMBL19475125 | 0.81 | FFAR4 (0.71) | FFAR4FFAR1FAAHGPR84NFKB1 | |
| SCHEMBL19475126 | 0.81 | FFAR4 (0.71) | FFAR4FFAR1FAAHGPR84NFKB1 | |
| Octadecanoic Acid Amide SCHEMBL5617445 | 0.81 | FFAR4 (0.71) | FFAR4FFAR1FAAHGPR84NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091107-A | RENAL VASODILATORS, ANTICLOTTING AGENTS, GROWTH HORMONE RELEASE, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |